Center for Neurologic Study-Lability Scale (CNS-LS)

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  • The CNS-LS is a short 7-item, self-administered questionnaire, designed to be completed by the patient, that provides a quantitative measure of the perceived frequency of pseudobulbar affect (PBA) episodes. The CNS-LS can help accurately diagnose PBA.
  • A CNS-LS score of 13 or higher may suggest PBA.
  • Sensitivity & Specificity:
    • Sensitivity: 74%
    • Specificity: 80%

Use the following EVALUATION FORM to evaluate your patient and PRINT THE FORM when the evaluation is completed.


1. Moore SR, Gresham LS, Bromberg MB, Kasarkis EJ, Smith RA. A self report measure of affective lability. J Neurol Neurosurg Psychiatry. 1997;63(1):89-93. 

2. Smith RA, Berg JE, Pope LE, Callahan JD, Wynn D, Thisted RA. Validation of the CNS emotional lability scale for pseudobulbar affect (pathological laughing and crying) in multiple sclerosis patients. Mult Scler. 2004;10(6):679-685.

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